White Matter Abnormalities Associated with Neurological Soft Signs in First-episode Schizophrenia: a Diffusion Tensor Imaging Study
نویسندگان
چکیده
C. Rodriguez-Régent, S. Mouchet-Mages, S. Rodrigo, M-O. Krebs, C. Oppenheim, and J-F. Meder Department of Morphologic and Functional Imaging, University Paris Descartes, Sainte Anne Hospital, PARIS, France, Pathophysiology of Psychiatric Diseases, University Paris Descartes, Sainte Anne Hospital, PARIS, France, Department of Morphologic and Functional Imaging, University Paris Descartes, Sainte Anne Hospital
منابع مشابه
Diffusion tensor imaging study of the fornix in first episode schizophrenia and in healthy controls.
BACKGROUND The fornix is a compact bundle of white matter fibers that project from the hippocampus to the mamillary bodies and septal nuclei. Its association with memory, as well as with symptoms in schizophrenia, has been reported in chronic schizophrenia. The purpose of this study is to determine whether or not fornix abnormalities are evident at the onset of schizophrenia. METHODS Diffusio...
متن کاملWhite matter abnormalities in first-episode schizophrenia or schizoaffective disorder: a diffusion tensor imaging study.
OBJECTIVE The goal of this study was to investigate brain white matter abnormalities by using diffusion tensor imaging in patients with schizophrenia or schizoaffective disorder close to illness onset. METHOD Ten patients experiencing a first episode of schizophrenia or schizoaffective disorder and 13 healthy volunteers received diffusion tensor imaging and structural magnetic resonance imagi...
متن کاملThe Benefits and implementations of Diffusion tensor imaging and Neural Fiber Tractography in Brain Surgery
Background and Aim: The methods for detecting brain activation with fMRI, MRI provides a way to measure the anatomical connections which enable lightning-fast communication among neurons that specialize in different kinds of brain functions. Diffusion tensor imaging is able to measure the direction of bundles of the axonal fibers which are all aligned. Besides mapping white matter fiber tracts,...
متن کاملComplementary diffusion tensor imaging study of the corpus callosum in patients with first-episode and chronic schizophrenia.
BACKGROUND Abnormalities in the corpus callosum have long been implicated in schizophrenia. Previous diffusion tensor imaging (DTI) studies in patients with different durations of schizophrenia yielded inconsistent results. By comparing patients with different durations of schizophrenia, we investigated if white matter abnormalities of the corpus callosum emerge at an early stage in the illness...
متن کاملExtensive white matter abnormalities in patients with first-episode schizophrenia: a Diffusion Tensor Iimaging (DTI) study.
BACKGROUND Previous voxelwise Diffusion Tensor Imaging (DTI) investigations of white matter in first-episode schizophrenia (FESZ) have been limited to the analysis of Fractional Anisotropy (FA) and mean diffusivity (MD), with their findings inconsistent in terms of the anatomical locations and extent of abnormalities. This study examines white matter abnormalities in FESZ, compared with healthy...
متن کامل